CW
Retatrutide purity was outstanding
Running metabolic assays with Retatrutide. Lot had >99% purity by reverse-phase HPLC — above spec. Mass spec confirmed molecular weight. Best peptide supplier we've worked with.
HPLC Verified
>98% Purity
COA Included
APEX Performance & Metabolic
AICAR
$65.1
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable AMP analogue and AMPK activator. Often called the ‘exercise pill’ in research literature, it mimics exercise adaptations in skeletal muscle via AMPK pathway activation without physical activity.
| Format | Lyophilized Vial |
|---|---|
| Dosage | 50mg |
| Purity | >98% |
| Sub-Line | APEX |
In Stock — Overnight and 2–3 day delivery available
Product Information
AICAR | AMPK Activator — Research Grade
AICAR (5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside) is a nucleoside analogue that is phosphorylated intracellularly to ZMP, an AMP mimetic that activates AMP-activated protein kinase (AMPK). It is one of the most widely used pharmacological AMPK activators in metabolic research.
Mechanism of Action
- AMPK activation — ZMP (intracellular product) mimics AMP, activating AMPK via allosteric binding and prevention of dephosphorylation
- Fatty acid oxidation — AMPK-mediated phosphorylation of ACC reduces malonyl-CoA, increasing mitochondrial fatty acid entry
- Glucose uptake — promotes GLUT4 translocation in skeletal muscle independent of insulin
- PGC-1alpha induction — drives mitochondrial biogenesis via PGC-1alpha, the master regulator of oxidative metabolism
Research Areas
AICAR is studied in metabolic syndrome, type 2 diabetes, exercise physiology, skeletal muscle adaptation, and longevity biology. It is frequently used alongside MOTS-c as an exercise-mimetic research tool.
For Research Use Only. Rainbow Peptide supplies AICAR exclusively for in vitro and laboratory research purposes. Not for human or veterinary use.
Frequently Asked Questions
- What is AICAR?
- AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable AMP analogue and AMPK activator. Often called the ‘exercise pill’ in research literature, it mimics exercise adaptations in skeletal muscle via AMPK pathway activation without physical activity.
- Is AICAR for sale at Rainbow Peptide?
- Yes. AICAR is available for purchase with Certificate of Analysis confirming >98% HPLC purity. Every order Overnight and 2–3 day delivery available. For Research Use Only.
- What purity is your AICAR?
- Rainbow Peptide's AICAR is >98% pure, HPLC verified by an accredited third-party laboratory. A COA is included with every order.
- Is AICAR safe for human use?
- No. AICAR is strictly For Research Use Only (RUO). It is not intended for human consumption and is not intended to diagnose, treat, cure, or prevent any disease.
- How quickly does AICAR ship?
- Overnight and 2–3 day delivery available. Ships in temperature-controlled packaging.
Third-Party Verified
Every Order Ships with a Certificate of Analysis
We don't just claim purity — we prove it. Every batch of AICAR is independently tested by an accredited third-party laboratory before it reaches you. Your COA is linked to your specific lot number.
- HPLC purity analysis — minimum threshold >98%
- Mass spectrometry — molecular weight confirmation
- Lot number traceable to your order
- Endotoxin limits verified — safe for cell-based assays
RAINBOW PEPTIDE LABS CERTIFICATE OF ANALYSIS
Product AICAR
Lot # RP-00048-A
HPLC Purity >98.0% >98.5% PASS
Mass Spec (MW) Confirmed Confirmed PASS
Endotoxin <1 EU/mg <0.5 EU/mg PASS
Visual Inspection White powder White powder PASS
What Researchers Say
Verified purchases from active research labs and scientists
5.00
★★★★★
2 verified reviews DP
Ipamorelin quality confirmed via QC
Internal verification confirmed COA data. Purity was 98.6% HPLC. Peptide behavior in our assay was consistent with published data. Will order again for next study phase.
BS
Consistent performance for research
AOD-9604 arrived quickly and in excellent condition. Cold pack preserved temperature. COA was thorough. Results in metabolic assays consistent with expected parameters.
