CW
Retatrutide purity was outstanding
Running metabolic assays with Retatrutide. Lot had >99% purity by reverse-phase HPLC, above spec. Mass spec confirmed molecular weight. Best peptide supplier we've worked with.
HPLC Verified
>98% Purity
COA Included
APEX Performance & Metabolic
AICAR
$65.1
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable AMP analogue and AMPK activator. Often called the ‘exercise pill’ in research literature, it mimics exercise adaptations in skeletal muscle via AMPK pathway activation without physical activity.
| Format | Lyophilized Vial |
|---|---|
| Dosage | 50mg |
| Purity | >98% |
| Sub-Line | APEX |
In Stock, Overnight and 2–3 day delivery available
Product Information
AICAR | AMPK Activator, Research Grade
AICAR (5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside) is a nucleoside analogue that is phosphorylated intracellularly to ZMP, an AMP mimetic that activates AMP-activated protein kinase (AMPK). It is one of the most widely used pharmacological AMPK activators in metabolic research.
Mechanism of Action
- AMPK activation, ZMP (intracellular product) mimics AMP, activating AMPK via allosteric binding and prevention of dephosphorylation
- Fatty acid oxidation, AMPK-mediated phosphorylation of ACC reduces malonyl-CoA, increasing mitochondrial fatty acid entry
- Glucose uptake, promotes GLUT4 translocation in skeletal muscle independent of insulin
- PGC-1alpha induction, drives mitochondrial biogenesis via PGC-1alpha, the master regulator of oxidative metabolism
Research Areas
AICAR is studied in metabolic syndrome, type 2 diabetes, exercise physiology, skeletal muscle adaptation, and longevity biology. It is frequently used alongside MOTS-c as an exercise-mimetic research tool.
Independent Lab Verification
Rainbow Peptide works with independent, accredited third-party laboratories, including Vanguard Laboratory (ISO 17025:2017-accredited, A2LA Certificate #6377.01.01), to verify compound identity and purity. A Certificate of Analysis is included with every order.
For Research Use Only. Rainbow Peptide supplies AICAR exclusively for in vitro and laboratory research purposes. Not for human or veterinary use.
Frequently Asked Questions
- What is AICAR?
- AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable AMP analogue and AMPK activator. Often called the ‘exercise pill’ in research literature, it mimics exercise adaptations in skeletal muscle via AMPK pathway activation without physical activity.
- Is AICAR for sale at Rainbow Peptide?
- Yes. AICAR is available for purchase with Certificate of Analysis confirming >98% HPLC purity. Every order Overnight and 2–3 day delivery available. For Research Use Only.
- What purity is your AICAR?
- Rainbow Peptide's AICAR is >98% pure, HPLC verified through independent third-party laboratory testing, including work performed by Vanguard Laboratory (ISO 17025:2017-accredited, A2LA Certificate #6377.01.01). A COA is included with every order.
- What does the Certificate of Analysis actually verify?
- A COA reports identity (confirming the compound is what it's labeled as, via HPLC-UV/VIS matched against a reference standard) and assay/content (the measured purity percentage). Together, this verifies a batch matches its labeled specification, rather than relying on a purity claim alone.
- Is AICAR safe for human use?
- No. AICAR is strictly For Research Use Only (RUO). It is not intended for human consumption and is not intended to diagnose, treat, cure, or prevent any disease.
- How quickly does AICAR ship?
- Overnight and 2–3 day delivery available. Ships in temperature-controlled packaging.
Third-Party Verified
Every Order Ships with a Certificate of Analysis
We don't just claim purity, we prove it. Every batch of AICAR is independently tested by an accredited third-party laboratory before it reaches you. Your COA is linked to your specific lot number.
- HPLC purity analysis, minimum threshold >98%
- Mass spectrometry, molecular weight confirmation
- Lot number traceable to your order
- Endotoxin limits verified, safe for cell-based assays
RAINBOW PEPTIDE LABS CERTIFICATE OF ANALYSIS
Product AICAR
Lot # RP-00048-A
HPLC Purity >98.0% >98.5% PASS
Mass Spec (MW) Confirmed Confirmed PASS
Endotoxin <1 EU/mg <0.5 EU/mg PASS
Visual Inspection White powder White powder PASS
What Researchers Say
Verified purchases from active research labs and scientists
5.00
★★★★★
2 verified reviews DP
Ipamorelin quality confirmed via QC
Internal verification confirmed COA data. Purity was 98.6% HPLC. Peptide behavior in our assay was consistent with published data. Will order again for next study phase.
BS
Consistent performance for research
AOD-9604 arrived quickly and in excellent condition. Cold pack preserved temperature. COA was thorough. Results in metabolic assays consistent with expected parameters.
