Ara 290 — Rainbow Peptide
🧪 HPLC Verified
>98% Purity
📄 COA Included
AXON Cognitive & Nootropic

ARA-290

$96.6

ARA-290 (cibinetide) is an 11-amino acid synthetic peptide derived from the non-erythropoietic region of erythropoietin. It selectively activates the innate repair receptor (IRR) without erythropoietic activity, studied in neuropathic pain, small fibre neuropathy, and sarcoidosis.

Format Lyophilized Vial
Dosage 16mg
Purity >98%
Sub-Line AXON

In Stock — Overnight and 2–3 day delivery available

Product Information

ARA-290 | Erythropoietin-Derived Tissue-Protective Peptide — Research Grade

ARA-290 (cibinetide) is a cyclic 11-amino acid peptide derived from the B-C loop of erythropoietin. It activates the innate repair receptor (IRR), a heterodimer of the EPO receptor and the beta-common receptor, without engaging classic EPO receptor homodimers responsible for erythropoiesis.

Mechanism of Action

  • IRR activation — selective agonism of the innate repair receptor triggers tissue-protective and anti-inflammatory signalling
  • No erythropoiesis — does not stimulate red blood cell production or elevate haematocrit, unlike full EPO
  • Neuroprotection — reduces apoptosis in dorsal root ganglion neurons in neuropathy models
  • Anti-inflammatory — decreases TNF-alpha, IL-6 and promotes regulatory T-cell activity in inflammatory models

Research Areas

ARA-290 has been studied in Phase II clinical trials for sarcoidosis-associated small fibre neuropathy, diabetic peripheral neuropathy, and chronic pain. European Phase II data showed significant improvement in corneal nerve fibre density and neuropathic pain scores.

For Research Use Only. Rainbow Peptide supplies ARA-290 exclusively for in vitro and laboratory research purposes. Not for human or veterinary use.

Frequently Asked Questions

What is ARA-290?
ARA-290 (cibinetide) is an 11-amino acid synthetic peptide derived from the non-erythropoietic region of erythropoietin. It selectively activates the innate repair receptor (IRR) without erythropoietic activity, studied in neuropathic pain, small fibre neuropathy, and sarcoidosis.
Is ARA-290 for sale at Rainbow Peptide?
Yes. ARA-290 is available for purchase with Certificate of Analysis confirming >98% HPLC purity. Every order Overnight and 2–3 day delivery available. For Research Use Only.
What purity is your ARA-290?
Rainbow Peptide's ARA-290 is >98% pure, HPLC verified by an accredited third-party laboratory. A COA is included with every order.
Is ARA-290 safe for human use?
No. ARA-290 is strictly For Research Use Only (RUO). It is not intended for human consumption and is not intended to diagnose, treat, cure, or prevent any disease.
How quickly does ARA-290 ship?
Overnight and 2–3 day delivery available. Ships in temperature-controlled packaging.

Third-Party Verified

Every Order Ships with a Certificate of Analysis

We don't just claim purity — we prove it. Every batch of ARA-290 is independently tested by an accredited third-party laboratory before it reaches you. Your COA is linked to your specific lot number.

  • HPLC purity analysis — minimum threshold >98%
  • Mass spectrometry — molecular weight confirmation
  • Lot number traceable to your order
  • Endotoxin limits verified — safe for cell-based assays
RAINBOW PEPTIDE LABS CERTIFICATE OF ANALYSIS
Product ARA-290
Lot # RP-00049-A
HPLC Purity >98.0% >98.5% PASS
Mass Spec (MW) Confirmed Confirmed PASS
Endotoxin <1 EU/mg <0.5 EU/mg PASS
Visual Inspection White powder White powder PASS

What Researchers Say

Verified purchases from active research labs and scientists

5.00
2 verified reviews
LP
Dr. L. Petrov Neuroplasticity Assay
★★★★★

Highest purity Selank we've sourced

This lot had 99.1% purity per our LC-MS verification. Batch traceable to the COA provided. Will be our go-to source for all cognitive peptide research going forward.

JA
J. Aldridge Neuroprotection Model
★★★★★

Consistent quality for cognitive research

Semax lot tested above spec. Excellent solubility, expected in vitro behavior. The detailed COA makes this compliant with our supplier verification protocol.

PW
P. Winters Ion Channel Study
★★★★

Good purity, great documentation

Mass spec and HPLC data attached to COA. Our internal QC confirmed results. Packaging was excellent — arrived at correct temperature with cold pack still active.