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Exceptional purity for peptide research
We've been sourcing research-grade peptides for several years. Rainbow Peptide's vials consistently pass our HPLC verification — purity exceeds 98% every batch. COA matched our internal testing exactly.
HPLC Verified
>98% Purity
COA Included
SOMA Recovery & Tissue Repair
Enclomiphene Powder 1g
$49.88
Enclomiphene (trans-clomiphene) powder 1g — ≥98% HPLC purity, COA verified. Non-steroidal selective estrogen receptor modulator studied for HPTA axis restoration and testosterone research. For research use only.
In Stock — Overnight and 2–3 day delivery available
Product Information
Enclomiphene Powder — Research Overview
Enclomiphene is the trans-isomer of clomiphene citrate (the active isomeric component), a non-steroidal selective estrogen receptor modulator (SERM) studied for testosterone restoration via HPTA axis modulation. Unlike clomiphene citrate (a 62:38 mixture of zuclomiphene:enclomiphene), enclomiphene as an isolated isomer has distinct pharmacokinetics and a cleaner estrogen receptor antagonism profile relevant for gonadotropin research.
Mechanism of Action
Enclomiphene acts as an estrogen receptor antagonist in the hypothalamus and pituitary gland, blocking the negative feedback of estradiol on GnRH and LH/FSH secretion. This disinhibition of the HPTA axis increases LH and FSH pulse amplitude and frequency, driving endogenous testicular testosterone production. Unlike exogenous testosterone, enclomiphene preserves spermatogenesis — a key distinction for male reproductive endocrinology research.
HPTA Research Applications
Enclomiphene is used in: hypogonadism mechanism research, HPTA axis recovery modelling (post-exogenous androgen suppression), male fertility and spermatogenesis studies, and estrogen receptor pharmacology in CNS and reproductive tissue. Phase II/III clinical data (Wiehle et al., 2014) demonstrated normalisation of testosterone in secondary hypogonadal men with preserved sperm parameters — providing a validated human reference dataset.
Isomeric Purity vs Clomiphene Citrate
Research using isolated enclomiphene (vs. racemic clomiphene) enables cleaner mechanistic data by eliminating confounding effects of zuclomiphene, which has longer half-life and partial ER agonist activity. This makes enclomiphene powder the preferred tool compound for SERM receptor selectivity studies.
Powder Format for Research
Soluble in DMSO (≥50mg/mL) and ethanol. For in vitro ER antagonism assays, cell-free receptor binding, and in vivo rodent HPTA studies. Standard rodent dosing: 1–10mg/kg/day oral.
Purity: ≥98% (HPLC verified) | Format: Lyophilised powder | Quantity: 1g
For research use only. Not for human consumption.
Frequently Asked Questions
- What is Enclomiphene Powder 1g?
- Enclomiphene (trans-clomiphene) powder 1g — ≥98% HPLC purity, COA verified. Non-steroidal selective estrogen receptor modulator studied for HPTA axis restoration and testosterone research. For research use only.
- Is Enclomiphene Powder 1g for sale at Rainbow Peptide?
- Yes. Enclomiphene Powder 1g is available for purchase with Certificate of Analysis confirming >98% HPLC purity. Every order Overnight and 2–3 day delivery available. For Research Use Only.
- What purity is your Enclomiphene Powder 1g?
- Rainbow Peptide's Enclomiphene Powder 1g is >98% pure, HPLC verified by an accredited third-party laboratory. A COA is included with every order.
- Is Enclomiphene Powder 1g safe for human use?
- No. Enclomiphene Powder 1g is strictly For Research Use Only (RUO). It is not intended for human consumption and is not intended to diagnose, treat, cure, or prevent any disease.
- How quickly does Enclomiphene Powder 1g ship?
- Overnight and 2–3 day delivery available. Ships in temperature-controlled packaging.
Third-Party Verified
Every Order Ships with a Certificate of Analysis
We don't just claim purity — we prove it. Every batch of Enclomiphene Powder 1g is independently tested by an accredited third-party laboratory before it reaches you. Your COA is linked to your specific lot number.
- HPLC purity analysis — minimum threshold >98%
- Mass spectrometry — molecular weight confirmation
- Lot number traceable to your order
- Endotoxin limits verified — safe for cell-based assays
RAINBOW PEPTIDE LABS CERTIFICATE OF ANALYSIS
Product Enclomiphene Powder 1g
Lot # RP-00404-A
HPLC Purity >98.0% >98.5% PASS
Mass Spec (MW) Confirmed Confirmed PASS
Endotoxin <1 EU/mg <0.5 EU/mg PASS
Visual Inspection White powder White powder PASS
What Researchers Say
Verified purchases from active research labs and scientists
5.00
★★★★★
2 verified reviews MT
Reliable consistency batch to batch
Third order now. Consistent batch-to-batch results matter enormously in long-term research. Certificate of Analysis is detailed with mass spec data. Would not switch sources.
SK
Solid product, shipping was fast
Verified against our reference standards. Purity >98.2% by HPLC. Packaging was appropriate for temperature-sensitive peptides. Will re-order.
