CW
Retatrutide purity was outstanding
Running metabolic assays with Retatrutide. Lot had >99% purity by reverse-phase HPLC — above spec. Mass spec confirmed molecular weight. Best peptide supplier we've worked with.
HPLC Verified
>98% Purity
COA Included
APEX Performance & Metabolic
Fragment 176-191
$42.68
HGH Fragment 176-191 is the 16-amino acid C-terminal fragment of human growth hormone spanning residues 176-191. It selectively activates beta-3 adrenergic receptors for lipolysis without GH receptor binding, making it a precise tool in fat metabolism research.
| Format | Lyophilized Vial |
|---|---|
| Dosage | 5mg |
| Purity | >98% |
| Sub-Line | APEX |
In Stock — Overnight and 2–3 day delivery available
Product Information
HGH Fragment 176-191 | Selective Lipolytic Peptide — Research Grade
HGH Fragment 176-191 corresponds to residues 176-191 of human growth hormone and contains the region responsible for GH lipolytic activity. A disulfide bond between Cys182 and Cys189 maintains the bioactive conformation. It has received FDA GRAS status and has been evaluated in Phase II obesity trials.
Mechanism of Action
- Beta-3 adrenergic activation — stimulates lipolysis in adipocytes via beta-3-AR pathway, not GH receptor
- ACC inhibition — reduces de novo lipogenesis by inhibiting acetyl-CoA carboxylase
- No GHR binding — does not activate the growth hormone receptor or alter IGF-1 or insulin levels
Research Areas
Studied in fat metabolism, obesity (Phase II RCT data available), osteoarthritis (Phase IIa), and as a selective lipolytic tool separate from full GH bioactivity research.
For Research Use Only. Rainbow Peptide supplies Fragment 176-191 exclusively for in vitro and laboratory research purposes. Not for human or veterinary use.
Frequently Asked Questions
- What is Fragment 176-191?
- HGH Fragment 176-191 is the 16-amino acid C-terminal fragment of human growth hormone spanning residues 176-191. It selectively activates beta-3 adrenergic receptors for lipolysis without GH receptor binding, making it a precise tool in fat metabolism research.
- Is Fragment 176-191 for sale at Rainbow Peptide?
- Yes. Fragment 176-191 is available for purchase with Certificate of Analysis confirming >98% HPLC purity. Every order Overnight and 2–3 day delivery available. For Research Use Only.
- What purity is your Fragment 176-191?
- Rainbow Peptide's Fragment 176-191 is >98% pure, HPLC verified by an accredited third-party laboratory. A COA is included with every order.
- Is Fragment 176-191 safe for human use?
- No. Fragment 176-191 is strictly For Research Use Only (RUO). It is not intended for human consumption and is not intended to diagnose, treat, cure, or prevent any disease.
- How quickly does Fragment 176-191 ship?
- Overnight and 2–3 day delivery available. Ships in temperature-controlled packaging.
Third-Party Verified
Every Order Ships with a Certificate of Analysis
We don't just claim purity — we prove it. Every batch of Fragment 176-191 is independently tested by an accredited third-party laboratory before it reaches you. Your COA is linked to your specific lot number.
- HPLC purity analysis — minimum threshold >98%
- Mass spectrometry — molecular weight confirmation
- Lot number traceable to your order
- Endotoxin limits verified — safe for cell-based assays
RAINBOW PEPTIDE LABS CERTIFICATE OF ANALYSIS
Product Fragment 176-191
Lot # RP-00036-A
HPLC Purity >98.0% >98.5% PASS
Mass Spec (MW) Confirmed Confirmed PASS
Endotoxin <1 EU/mg <0.5 EU/mg PASS
Visual Inspection White powder White powder PASS
What Researchers Say
Verified purchases from active research labs and scientists
5.00
★★★★★
2 verified reviews DP
Ipamorelin quality confirmed via QC
Internal verification confirmed COA data. Purity was 98.6% HPLC. Peptide behavior in our assay was consistent with published data. Will order again for next study phase.
BS
Consistent performance for research
AOD-9604 arrived quickly and in excellent condition. Cold pack preserved temperature. COA was thorough. Results in metabolic assays consistent with expected parameters.
