MV
GHK-Cu lot was outstanding
We use GHK-Cu in dermal fibroblast research. This lot performed exactly as expected — >98% purity HPLC. The COA cited the reference standard lot number. That detail is rare at this price point.
HPLC Verified
>98% Purity
COA Included
AURA Anti-Aging & Longevity
MOTS-C
$100.0
MOTS-c is a 16-amino acid mitochondria-derived peptide that regulates AMPK signalling, glucose metabolism, and exercise-mimicking pathways. Studied extensively in metabolic disease and longevity research.
| Format | Lyophilized Vial |
|---|---|
| Dosage | 10mg |
| Purity | >98% |
| Sub-Line | AURA |
Also available: MOTS-c Capsules (10mg) →
In Stock — Overnight and 2–3 day delivery available
Product Information
MOTS-c | Mitochondria-Derived Metabolic Peptide — Research Grade
MOTS-c is a 16-amino acid peptide encoded within the mitochondrial 12S rRNA gene (MT-RNR1), making it one of the few mitochondria-derived peptides (MDPs) identified in humans. It translocates to the nucleus during metabolic stress and directly modulates gene expression related to glucose homeostasis.
Mechanism of Action
- AMPK activation — activates AMP-activated protein kinase, the master metabolic switch governing glucose uptake and fatty acid oxidation
- Folate cycle modulation — inhibits the folate cycle and de novo purine synthesis, triggering AICAR accumulation and downstream AMPK signalling
- Exercise-mimicking — plasma levels increase with physical exercise; supplementation mimics exercise-like metabolic adaptations in rodent models
- Insulin sensitisation — improves insulin sensitivity in high-fat diet and diabetic rodent models
Research Areas
MOTS-c is studied in type 2 diabetes, obesity, exercise physiology, skeletal muscle metabolism, and longevity/ageing biology. Circulating MOTS-c levels decline with age, making it a candidate for ageing research interventions.
For Research Use Only. Rainbow Peptide supplies MOTS-c exclusively for in vitro and laboratory research purposes. Not for human or veterinary use.
Frequently Asked Questions
- What is MOTS-C?
- MOTS-c is a 16-amino acid mitochondria-derived peptide that regulates AMPK signalling, glucose metabolism, and exercise-mimicking pathways. Studied extensively in metabolic disease and longevity research.
- Is MOTS-C for sale at Rainbow Peptide?
- Yes. MOTS-C is available for purchase with Certificate of Analysis confirming >98% HPLC purity. Every order Overnight and 2–3 day delivery available. For Research Use Only.
- What purity is your MOTS-C?
- Rainbow Peptide's MOTS-C is >98% pure, HPLC verified by an accredited third-party laboratory. A COA is included with every order.
- Is MOTS-C safe for human use?
- No. MOTS-C is strictly For Research Use Only (RUO). It is not intended for human consumption and is not intended to diagnose, treat, cure, or prevent any disease.
- How quickly does MOTS-C ship?
- Overnight and 2–3 day delivery available. Ships in temperature-controlled packaging.
Third-Party Verified
Every Order Ships with a Certificate of Analysis
We don't just claim purity — we prove it. Every batch of MOTS-C is independently tested by an accredited third-party laboratory before it reaches you. Your COA is linked to your specific lot number.
- HPLC purity analysis — minimum threshold >98%
- Mass spectrometry — molecular weight confirmation
- Lot number traceable to your order
- Endotoxin limits verified — safe for cell-based assays
RAINBOW PEPTIDE LABS CERTIFICATE OF ANALYSIS
Product MOTS-C
Lot # RP-00039-A
HPLC Purity >98.0% >98.5% PASS
Mass Spec (MW) Confirmed Confirmed PASS
Endotoxin <1 EU/mg <0.5 EU/mg PASS
Visual Inspection White powder White powder PASS
What Researchers Say
Verified purchases from active research labs and scientists
5.00
★★★★★
2 verified reviews NF
Best Epithalon sourcing this quarter
Sourced Epithalon from three vendors this quarter. Rainbow Peptide had the most detailed COA and lowest endotoxin levels measured. Will be primary source for our current project.
HB
Good peptide, delivered fast
GHK-Cu arrived in 2 business days. Cold pack still active on delivery. Peptide dissolved cleanly in bacteriostatic water. COA was comprehensive. Happy with this purchase.
