5-Amino-1MQ Capsules (50mg)

5-Amino-1MQ Capsules | NNMT Inhibitor — Metabolic Research

5-Amino-1MQ (5-Amino-1-methylquinolinium) is a cell-permeable, orally bioavailable small molecule that potently inhibits nicotinamide N-methyltransferase (NNMT), an enzyme highly expressed in white adipose tissue. Preclinical studies have reported significant fat mass reduction, increased energy expenditure, and enhanced NAD+ metabolite levels. These capsules (50mg per capsule, 60 capsules) provide standardised dosing for chronic metabolic research protocols.

Mechanism of Action

• NNMT inhibition — blocks methylation of nicotinamide, redirecting methyl groups and increasing SAM (S-adenosylmethionine) availability
• NAD+ pathway activation — elevates NAD+ precursor levels and downstream sirtuin activity
• Adipogenesis suppression — impairs adipocyte differentiation and lipid accumulation in cell models
• Energy expenditure — increases thermogenesis markers and mitochondrial activity in adipose tissue models

Research Areas

5-Amino-1MQ is studied in obesity, metabolic syndrome, NAFLD, and NAD+ biology research. Commonly paired with NAD+ and AICAR in multi-pathway metabolic studies. The capsule format supports longer-duration adipocyte and metabolic adaptation research protocols.

For Research Use Only. Rainbow Peptide supplies this compound exclusively for in vitro and laboratory research purposes. Not for human or veterinary use.